Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PER2 | O15055 | 1/20 | 0.31 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577938 | 1.00 | MAPT (0.33) | MAPTGAAMAP3K5HTR6POLB | |
| SCHEMBL23601076 | 0.89 | MAPT (0.39) | MAPTGAAMAP3K5POLBSMN1; SMN2 | |
| SCHEMBL23576677 | 0.83 | PIK3CA (0.32) | PIK3CAPIK3CBPIK3CG | |
| SCHEMBL29909207 | 0.83 | PIK3CA (0.32) | PIK3CAPIK3CBPIK3CG | |
| SCHEMBL23576783 | 0.82 | MAPT (0.38) | MAPTHTR6POLBSMN1; SMN2 | |
| SCHEMBL29909809 | 0.82 | MAPT (0.38) | MAPTHTR6POLBSMN1; SMN2 | |
| SCHEMBL23601741 | 0.81 | SMN1; SMN2 (0.32) | MAPTSMN1; SMN2PER2CRY2 | |
| SCHEMBL23601843 | 0.81 | MAPT (0.32) | MAPTSMN1; SMN2 | |
| SCHEMBL23577851 | 0.81 | MAP3K14 (0.31) | MAPT | |
| SCHEMBL24721316 | 0.81 | SMN1; SMN2 (0.32) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |