SCHEMBL29909216

SCHEMBL29909216

CN(c1cccc(-c2ccc(C3(C#N)CCC3)nc2)c1)c1nc2nncn2c2cc(Cl)ccc12

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.32
FNTB P49356 1/20 0.32
HRH4 Q9H3N8 1/20 0.31
MAP4K4 O95819 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23577231 1.00 FNTA (0.32) FNTAFNTBHRH4MAP4K4
SCHEMBL29909295 0.97 FNTA (0.33) FNTAFNTBHRH4
SCHEMBL23576859 0.97 FNTA (0.33) FNTAFNTBHRH4
SCHEMBL23601244 0.89 FNTA (0.33) FNTAFNTBHRH4
SCHEMBL23601231 0.86 ALDH1A1 (0.33) FNTAFNTBHRH4MAP4K4
SCHEMBL31169411 0.86 ALDH1A1 (0.33) FNTAFNTBHRH4MAP4K4
SCHEMBL29909068 0.86 ABCG2 (0.30)
SCHEMBL24721614 0.86 ABCG2 (0.30)
SCHEMBL23601815 0.84 FNTA (0.33) FNTAFNTBHRH4
SCHEMBL23601028 0.82 FNTA (0.36) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4445902-A2 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2024-10-16 EP disclosed
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed