SCHEMBL29909295

SCHEMBL29909295

CN(c1cccc(-c2ccc(C3(C#N)CC3)nc2)c1)c1nc2nncn2c2cc(Cl)ccc12

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
HRH4 Q9H3N8 1/20 0.32
MAT2A P31153 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23576859 1.00 FNTA (0.33) FNTAFNTBHRH4MAT2A
SCHEMBL29909216 0.97 FNTA (0.32) FNTAFNTBHRH4
SCHEMBL23577231 0.97 FNTA (0.32) FNTAFNTBHRH4
SCHEMBL31169411 0.89 ALDH1A1 (0.33) FNTAFNTBHRH4MAT2A
SCHEMBL23601231 0.89 ALDH1A1 (0.33) FNTAFNTBHRH4MAT2A
SCHEMBL24721614 0.89 ABCG2 (0.30)
SCHEMBL29909068 0.89 ABCG2 (0.30)
SCHEMBL23601244 0.87 FNTA (0.33) FNTAFNTBHRH4MAT2A
SCHEMBL23601815 0.86 FNTA (0.33) FNTAFNTBHRH4
SCHEMBL23601028 0.83 FNTA (0.36) FNTAFNTBMAT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed