SCHEMBL29909246

SCHEMBL29909246

CN(c1cc(F)cc(-c2ccccc2)c1C(F)F)c1nc2nnc(Cl)n2c2ccccc12

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.32
DHODH Q02127 1/20 0.32
MAT2A P31153 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29909510 0.78
SCHEMBL29909492 0.77
SCHEMBL30961017 0.76 ABCG2 (0.34) ABCG2
SCHEMBL29909479 0.75 ABCG2 (0.31) ABCG2
SCHEMBL29909643 0.74 ABCG2 (0.37) ABCG2DHODH
SCHEMBL29909322 0.72 ABCG2 (0.35) ABCG2
SCHEMBL29909535 0.71 SLC6A2 (0.31) MAT2A
SCHEMBL30961042 0.71
SCHEMBL29909705 0.71 ABCG2 (0.37) ABCG2DHODH
SCHEMBL29909871 0.71 ABCG2 (0.40) ABCG2DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed