SCHEMBL29909479

SCHEMBL29909479

CN(c1ccc(F)c(-c2ccc(C(F)F)cc2)c1)c1nc2nnc(Cl)n2c2ccccc12

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29909643 0.86 ABCG2 (0.37) ABCG2
SCHEMBL29909690 0.86 ABCG2 (0.31) ABCG2
SCHEMBL29909492 0.85
SCHEMBL30961017 0.84 ABCG2 (0.34) ABCG2
SCHEMBL29909510 0.83
SCHEMBL29909406 0.78 ABCG2 (0.36) ABCG2
SCHEMBL23577556 0.78 ADORA2A (0.33)
SCHEMBL29909092 0.77 ALOX5AP (0.31)
SCHEMBL29909331 0.76 ADORA3 (0.34)
SCHEMBL29909705 0.76 ABCG2 (0.37) ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12054490-B2 Diacylglycerol kinase modulating compounds GILEAD SCIENCES, INC. (US) 2024-08-06 US disclosed
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12054490-B2 Diacylglycerol kinase modulating compounds DGKG, DGKB, DGKK ABCG2 4216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.