Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.37 |
| ▸ | PDE5A | O76074 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909747 | 0.91 | ABCG2 (0.36) | ABCG2DHODH | |
| SCHEMBL29909551 | 0.90 | CYP11B2 (0.31) | CYP11B2 | |
| SCHEMBL29909708 | 0.88 | ABCG2 (0.41) | ABCG2PDE5ACYP11B2NPC1POLB | |
| SCHEMBL29909353 | 0.87 | ABCG2 (0.37) | ABCG2PDE5ANPC1POLBGAA | |
| SCHEMBL29909643 | 0.87 | ABCG2 (0.37) | ABCG2PDE5ADHODHGRIN1GRIN2B | |
| SCHEMBL29909741 | 0.86 | NPC1 (0.43) | ABCG2PDE5ANPC1POLBGAA | |
| SCHEMBL29909758 | 0.86 | ABCG2 (0.37) | ABCG2PDE5ADHODHGRIN2B | |
| SCHEMBL29909687 | 0.86 | ABCG2 (0.37) | ABCG2PDE5ADHODH | |
| SCHEMBL29909361 | 0.85 | HSD17B1 (0.39) | ABCG2PDE5A | |
| SCHEMBL29909750 | 0.84 | ABCG2 (0.36) | ABCG2PDE5ANPC1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |