SCHEMBL29909261

SCHEMBL29909261

CN(c1cccc(C#CC2CC2)c1)c1nc2nnc(Cl)n2c2ccc(F)cc12

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.32
GSK3B P49841 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29909076 0.92 GRM5 (0.34) ABCG2
SCHEMBL29909337 0.85 ABCG2 (0.34) ABCG2
SCHEMBL23577280 0.84 ABCG2 (0.33) ABCG2GSK3B
SCHEMBL29909299 0.84 ABCG2 (0.33) ABCG2GSK3B
SCHEMBL29909252 0.84 ABCG2 (0.45) ABCG2
SCHEMBL29909898 0.81
SCHEMBL29909871 0.81 ABCG2 (0.40) ABCG2
SCHEMBL29909513 0.77 ABCG2 (0.35) ABCG2
SCHEMBL23601314 0.77
SCHEMBL29909128 0.76 ABCG2 (0.34) ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324767-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2024-07-12 CN disclosed
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed