Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HK1 | P19367 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909871 | 0.92 | ABCG2 (0.40) | ABCG2DHODHMAPTHK1HTT | |
| SCHEMBL29909148 | 0.85 | DHODH (0.39) | ABCG2DHODH | |
| SCHEMBL29909909 | 0.84 | DHODH (0.41) | ABCG2DHODH | |
| SCHEMBL29909452 | 0.84 | DHODH (0.38) | ABCG2DHODH | |
| SCHEMBL29909261 | 0.84 | ABCG2 (0.32) | ABCG2 | |
| SCHEMBL29909747 | 0.83 | ABCG2 (0.36) | ABCG2DHODH | |
| SCHEMBL29909783 | 0.83 | DHODH (0.37) | ABCG2DHODH | |
| SCHEMBL29909337 | 0.83 | ABCG2 (0.34) | ABCG2DHODH | |
| SCHEMBL29909893 | 0.82 | ABCG2 (0.35) | ABCG2DHODH | |
| SCHEMBL29909388 | 0.80 | ABCG2 (0.40) | ABCG2DHODHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |