Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | C1R | P00736 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577291 | 1.00 | MAPT (0.43) | MAPTLMNATDP1MEN1KMT2A | |
| SCHEMBL16208399 | 0.86 | MAPT (0.41) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL27235793 | 0.85 | MAPT (0.41) | MAPTLMNATDP1MEN1KMT2A | |
| SCHEMBL23601680 | 0.84 | NPC1 (0.43) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL16208398 | 0.84 | RAB9A (0.43) | MAPTLMNATDP1MEN1KMT2A | |
| SCHEMBL29909620 | 0.82 | NPC1 (0.41) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL23576644 | 0.82 | NPC1 (0.41) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL23576960 | 0.79 | NPC1 (0.49) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL30013472 | 0.79 | NPC1 (0.49) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL20401044 | 0.78 | MAPT (0.60) | MAPTLMNATDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |