Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577571 | 1.00 | GAA (0.34) | GAAALDH1A1MAPTAPPDHODH | |
| SCHEMBL23577618 | 0.84 | ABCG2 (0.35) | ALDH1A1MAPTDHODHABCG2EGFR | |
| SCHEMBL30013647 | 0.84 | ABCG2 (0.35) | ALDH1A1MAPTDHODHABCG2EGFR | |
| SCHEMBL30013703 | 0.78 | EGFR (0.41) | GAAMAPTEGFRCSF1RMEN1 | |
| SCHEMBL23576846 | 0.78 | EGFR (0.41) | GAAMAPTEGFRCSF1RMEN1 | |
| SCHEMBL23576718 | 0.76 | ABCG2 (0.47) | ABCG2 | |
| SCHEMBL23601686 | 0.74 | MEN1 (0.48) | GAAMAPTEGFRCSF1RMEN1 | |
| SCHEMBL23601525 | 0.73 | PTGS2 (0.31) | — | |
| SCHEMBL23576651 | 0.72 | MMP13 (0.30) | — | |
| SCHEMBL29909359 | 0.72 | MMP13 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |