Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577546 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2ABCG2TP53PDE5AFNTA | |
| SCHEMBL23577126 | 0.91 | TACR1 (0.40) | SMN1; SMN2ABCG2PDE5AFNTAFNTB | |
| SCHEMBL29909622 | 0.91 | TACR1 (0.40) | SMN1; SMN2ABCG2PDE5AFNTAFNTB | |
| SCHEMBL23578033 | 0.90 | PDE5A (0.44) | SMN1; SMN2ABCG2PDE5AALDH1A1KDM4E | |
| SCHEMBL23578009 | 0.89 | ALDH1A1 (0.39) | SMN1; SMN2ABCG2TP53PDE5AALDH1A1 | |
| SCHEMBL29909882 | 0.89 | ALDH1A1 (0.39) | SMN1; SMN2ABCG2TP53PDE5AALDH1A1 | |
| SCHEMBL23576887 | 0.88 | DHODH (0.40) | SMN1; SMN2ABCG2TP53FNTAFNTB | |
| SCHEMBL29909316 | 0.88 | DHODH (0.40) | SMN1; SMN2ABCG2TP53FNTAFNTB | |
| SCHEMBL23577059 | 0.88 | FNTA (0.41) | TP53FNTAFNTBOPRD1MAPT | |
| SCHEMBL23576713 | 0.88 | OPRD1 (0.34) | SMN1; SMN2ABCG2TP53FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-B1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES INC (JP) | 2024-09-18 | — | — | EP | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |