Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 3/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577502 | 1.00 | PTGES (0.38) | PTGESNPC1RAB9APOLBNR2F2 | |
| SCHEMBL23600999 | 0.99 | PTGES (0.39) | PTGESNPC1RAB9APOLBNR2F2 | |
| SCHEMBL29909225 | 0.99 | PTGES (0.39) | PTGESNPC1RAB9APOLBNR2F2 | |
| SCHEMBL29909373 | 0.97 | PTGES (0.37) | PTGESNPC1RAB9APOLBNR2F2 | |
| SCHEMBL23578417 | 0.97 | PTGES (0.37) | PTGESNPC1RAB9APOLBNR2F2 | |
| SCHEMBL23576967 | 0.90 | GRM5 (0.33) | PTGESMAP3K14GRM5 | |
| SCHEMBL29909449 | 0.89 | GRM5 (0.31) | PTGESMAP3K14GRM5 | |
| SCHEMBL23577431 | 0.89 | GRM5 (0.31) | PTGESMAP3K14GRM5 | |
| SCHEMBL23577106 | 0.89 | MAP3K14 (0.32) | PTGESMAP3K14GRM5 | |
| SCHEMBL23601000 | 0.85 | MAT2A (0.32) | MAT2APRMT5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |