Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.43 |
| ▸ | KDR | P35968 | 4/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP14 | P31944 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | CASP4 | P49662 | 1/20 | 0.39 |
| ▸ | CASP5 | P51878 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP9 | P55211 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.39 |
| ▸ | CASP12 | Q6UXS9 | 1/20 | 0.39 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909273 | 0.85 | ABCG2 (0.36) | EGFRPDGFRBKDR | |
| SCHEMBL30979132 | 0.84 | EGFR (0.43) | EGFRKDR | |
| SCHEMBL30979122 | 0.83 | PDE5A (0.43) | EGFRPDGFRBKDR | |
| SCHEMBL29909428 | 0.82 | ABCG2 (0.34) | EGFR | |
| SCHEMBL29909694 | 0.81 | CYP1A1 (0.35) | CSF1REGFR | |
| SCHEMBL23578005 | 0.80 | ALDH1A1 (0.48) | CSF1REGFRPDGFRBKDRCASP1 | |
| SCHEMBL29909588 | 0.80 | ALDH1A1 (0.48) | CSF1REGFRPDGFRBKDRCASP1 | |
| SCHEMBL29909748 | 0.75 | SCN9A (0.40) | CSF1REGFRHPGD | |
| SCHEMBL30979049 | 0.75 | ABCG2 (0.43) | EGFRPDGFRBKDR | |
| SCHEMBL29909731 | 0.74 | ABCG2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |