Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.33 |
| ▸ | PDE5A | O76074 | 2/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30979132 | 0.84 | EGFR (0.43) | ABCG2PDE5ACSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL29909273 | 0.83 | ABCG2 (0.36) | ABCG2PDE5ACSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL30979122 | 0.81 | PDE5A (0.43) | ABCG2PDE5ACSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL29909368 | 0.81 | CSF1R (0.45) | EGFRCSF1R | |
| SCHEMBL29909000 | 0.81 | CYP1A1 (0.39) | CYP1A1CYP1A2CYP1B1ABCG2PDE5A | |
| SCHEMBL23577064 | 0.81 | CYP1A1 (0.39) | CYP1A1CYP1A2CYP1B1ABCG2PDE5A | |
| SCHEMBL29909428 | 0.81 | ABCG2 (0.34) | ABCG2PDE5ACSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL30979049 | 0.75 | ABCG2 (0.43) | ABCG2EGFR | |
| SCHEMBL29909731 | 0.73 | ABCG2 (0.46) | ABCG2CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL23601201 | 0.73 | GRM5 (0.36) | ABCG2PDE5ACSNK2A1CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |