Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909252 | 0.80 | ABCG2 (0.45) | ABCG2DHODHMAPT | |
| SCHEMBL29909866 | 0.80 | PDE5A (0.37) | ABCG2 | |
| SCHEMBL29909958 | 0.74 | ABCG2 (0.48) | ABCG2MAPT | |
| SCHEMBL23577733 | 0.74 | ABCG2 (0.38) | ABCG2 | |
| SCHEMBL29909082 | 0.73 | ABCG2 (0.37) | ABCG2KDM4EMAPTMAPK1L3MBTL1 | |
| SCHEMBL30978989 | 0.73 | ABCG2 (0.40) | ABCG2DHODH | |
| SCHEMBL29909871 | 0.73 | ABCG2 (0.40) | ABCG2DHODHMAPT | |
| SCHEMBL29909261 | 0.72 | ABCG2 (0.32) | ABCG2 | |
| SCHEMBL30978997 | 0.71 | PDE5A (0.36) | ABCG2ALDH1A1 | |
| SCHEMBL30979049 | 0.68 | ABCG2 (0.43) | ABCG2DHODHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |