SCHEMBL29909390

SCHEMBL29909390

C#CC(C)(O)Cc1cncc2c1CCCN2c1nc2nncn2c2ccc(F)cc12

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PER2 O15055 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23601486 0.87 PER2 (0.33) PER2
SCHEMBL29909608 0.87 PER2 (0.32) PER2
SCHEMBL23576973 0.84 PER2 (0.32) PER2
SCHEMBL23601409 0.84 PER2 (0.30) PER2
SCHEMBL23601016 0.82 MAPT (0.36)
SCHEMBL23577967 0.81 MAPT (0.31)
SCHEMBL30979164 0.81 MAPT (0.34) PER2
SCHEMBL23576649 0.81 MAPT (0.34) PER2
SCHEMBL23601416 0.80
SCHEMBL29909539 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324767-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2024-07-12 CN disclosed
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed