Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23578286 | 1.00 | KMT2A (0.49) | KMT2ASTAT3HRH4HRH3ATM | |
| SCHEMBL29909921 | 0.84 | STAT3 (0.54) | KMT2ASTAT3MAPTSMN1; SMN2HTT | |
| SCHEMBL23576676 | 0.84 | STAT3 (0.54) | KMT2ASTAT3MAPTSMN1; SMN2HTT | |
| SCHEMBL23601737 | 0.83 | KMT2A (0.53) | KMT2ASTAT3MAPTSMN1; SMN2MEN1 | |
| SCHEMBL29909671 | 0.83 | KMT2A (0.53) | KMT2ASTAT3MAPTSMN1; SMN2MEN1 | |
| SCHEMBL23576857 | 0.82 | KMT2A (0.51) | KMT2ASTAT3MAPTSMN1; SMN2HTT | |
| SCHEMBL29909597 | 0.82 | KMT2A (0.51) | KMT2ASTAT3MAPTSMN1; SMN2HTT | |
| SCHEMBL30979080 | 0.82 | KMT2A (0.63) | KMT2ASTAT3MAPTSMN1; SMN2MEN1 | |
| SCHEMBL23601720 | 0.82 | KMT2A (0.63) | KMT2ASTAT3MAPTSMN1; SMN2MEN1 | |
| SCHEMBL23601270 | 0.80 | STAT3 (0.51) | KMT2ASTAT3MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |