⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2085402 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL27816849 | 0.98 | EGFR (0.51) | — | |
| Hydrochloric Acid SCHEMBL8662102 | 0.81 | RAPGEF4 (0.48) | — | |
| SCHEMBL628205 | 0.81 | TSHR (0.61) | — | |
| SCHEMBL29961149 | 0.79 | RAPGEF4 (0.61) | — | |
| SCHEMBL790339 | 0.79 | MEN1 (0.52) | — | |
| SCHEMBL29961547 | 0.79 | RAPGEF4 (0.61) | — | |
| SCHEMBL1687027 | 0.79 | RAPGEF4 (0.61) | — | |
| Hydrochloric Acid SCHEMBL5151093 | 0.78 | TSHR (0.58) | — | |
| SCHEMBL6664529 | 0.78 | RAPGEF4 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747248-A1 | COMPOUNDS FOR USE IN A METHOD OF TARGETED PROTEIN DEGRADATION | Institute of Cancer Research: Royal Cancer Hospital (The) (GB) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025022093-A1 | COMPOUNDS FOR USE IN A METHOD OF TARGETED PROTEIN DEGRADATION | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2025-01-30 | — | — | WO | disclosed |
| EP-4359389-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-115557823-A | Method for synthesizing amide compound | 浙江工业大学 | 2023-01-03 | — | — | CN | disclosed |
| WO-2022271677-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| EP-4081199-A2 | LIPOXYGENASE INHIBITORS | SRI International (US) | 2022-11-02 | — | — | EP | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |