SCHEMBL628205

SCHEMBL628205

CNc1cccc(NC)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.61
MAPT P10636 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 1/20 0.48
AR P10275 1/20 0.48
APP P05067 1/20 0.42
BRD4 O60885 1/20 0.40
GPR35 Q9HC97 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HTT P42858 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
EGFR P00533 6/20 0.37
ERBB2 P04626 3/20 0.37
IDH2 P48735 1/20 0.36
EPHB2 P29323 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5151093 0.97 TSHR (0.58) TSHRMAPTMEN1KMT2AALDH1A1
SCHEMBL31231921 0.91 MAPT (0.62) TSHRMAPTMEN1KMT2AALDH1A1
SCHEMBL11485819 0.87 NOS1 (0.48) TSHRMAPTMEN1KMT2AALDH1A1
SCHEMBL10053831 0.87 TSHR (0.48) TSHRMAPTMEN1KMT2AALDH1A1
SCHEMBL23643414 0.84 MAPT (0.76) TSHRMAPTMEN1KMT2AALDH1A1
SCHEMBL29697291 0.83
SCHEMBL4974175 0.83
SCHEMBL306337 0.83
SCHEMBL23680234 0.83
SCHEMBL9312188 0.83 TDP1 (0.56) TSHRMAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 526 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250347039-A1 Fire protection composite made of a liquid applied coating and a mat or fleece for an electric vehicle battery HENKEL AG & CO KGAA (DE) 2025-11-13 US claimed
CN-120158100-A Preparation method of high-temperature-resistant corrosion-resistant alloy rubber 上海焦能新材料有限公司 2025-06-17 CN claimed
US-12234370-B2 Epoxy compositions CARBOLINE INTERNATIONAL CORPORATION (US) 2025-02-25 US claimed
EP-4504818-A1 A TWO-PART, ROOM TEMPERATURE CURABLE HEAT AND FIRE RETARDANT COMPOSITION Henkel AG & Co. KGaA (DE) 2025-02-12 EP claimed
CN-119306560-A Method for reducing polymer adhesion in ethylene oligomerization 万华化学集团股份有限公司 2025-01-14 CN claimed
US-20250011603-A1 Two-part, room temperature curable heat and fire retardant composition HENKEL AG & CO KGAA (DE) 2025-01-09 US claimed
US-12186714-B2 Reverse osmosis membrane and method of producing the same MEMSTAR USA INC. (US) 2025-01-07 US claimed
WO-2024261718-A1 USE OF SPECIFIC POLYESTER POLYOLS AS SOFT PHASE FOR THE PREPARATION OF REMOVABLE POLYURETHANE ADHESIVES AND USE OF SAID ADHESIVES G.P.S. TECH S.R.L. (IT) 2024-12-26 WO claimed
CN-118974133-A Two part room temperature curable heat and flame resistant composition 汉高股份有限及两合公司 2024-11-15 CN claimed
WO-2024165249-A1 A FIRE PROTECTION COMPOSITE MADE OF A LIQUID APPLIED COATING AND A MAT OR FLEECE FOR AN ELECTRIC VEHICLE BATTERY HENKEL AG & CO. KGAA (DE) 2024-08-15 WO claimed
US-20100278771-A1 Optically Clear Biofouling Resistant Compositions and Methods for Marine Instruments Mid-Mountain Materials, Inc 2010-11-04 US claimed
CN-101787065-A Cytarabine prodrug derivatives and purposes thereof in resisting cancers and tumors FENG GAO 2010-07-28 CN claimed
EP-1745096-B1 THERMOHARDENABLE EPOXY RESIN-BASED COMPOSITIONS, 3(4)-(AMINOMETHYL)-CYCLOHEXANE-PROPANAMINE AND 1,4(5)-CYCLOOCTANE DIMETHANAMINE EVONIK DEGUSSA GMBH (DE) 2008-04-30 EP claimed
US-20080027169-A1 Thermohardenable Epoxy Resin-Based Compositions, 3(4)-(Aminomethyl)-Cyclohexane-Propanamine and 1,4(5)-Cyclooctane Dimethanamine DEGUSSA AG (DE) 2008-01-31 US claimed
US-20060207930-A1 Interfacial composite structure and method of making them GENERAL ELECTRIC COMPANY 2006-09-21 US claimed
US-5693227-A POLYMERIZATION OF MOLECULES HAVING ELECTROPHILIC AND NUCLEOPHILIC SUBSTITUENTS ON THE SAME OR DIFFERENT MOLECULES; REGENERATION OF AMINOPYRIDINE CATALYSTS IONICS, INCORPORATED (US) 1997-12-02 US claimed
EP-0462967-B1 CHLORINE-RESISTANT SEMIPERMEABLE MEMBRANES AlliedSignal Inc. (US) 1992-11-25 EP claimed
US-4913816-A AMINE CROSSLINKED MULTILAYER POLYMER IONICS INCORPORATED (US) 1990-04-03 US claimed
EP-0227043-A2 Composite semipermeable membrane and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-07-01 EP claimed
US-4069206-A HYGROSCOPIC, PHOTOSENSITIVITY TEIJIN LIMITED (JA) 1978-01-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100278771-A1 Optically Clear Biofouling Resistant Compositions and Methods for Marine Instruments CRY1, CDH1, FHIT TSHR 3801/4885MAPT 1777/4885MEN1 1335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.