Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577153 | 1.00 | AOC3 (0.38) | AOC3PARP1DHODHTP53BACE1 | |
| SCHEMBL23576968 | 0.90 | TP53 (0.47) | AOC3TP53MTNR1AMTNR1BPLAU | |
| SCHEMBL29909468 | 0.90 | TP53 (0.47) | AOC3TP53MTNR1AMTNR1BPLAU | |
| SCHEMBL23577181 | 0.90 | IDO1 (0.37) | AOC3TP53MTNR1AMTNR1BPLAU | |
| SCHEMBL29909015 | 0.90 | IDO1 (0.37) | AOC3TP53MTNR1AMTNR1BPLAU | |
| SCHEMBL23601408 | 0.89 | KMT2A (0.39) | AOC3DHODHTP53MTNR1AMTNR1B | |
| SCHEMBL29909110 | 0.89 | KMT2A (0.39) | AOC3DHODHTP53MTNR1AMTNR1B | |
| SCHEMBL29909696 | 0.88 | TP53 (0.35) | AOC3PARP1DHODHTP53MTNR1A | |
| SCHEMBL23576961 | 0.88 | TP53 (0.35) | AOC3PARP1DHODHTP53MTNR1A | |
| SCHEMBL23576886 | 0.88 | FGFR1 (0.35) | AOC3DHODHTP53MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |