⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601758 | 1.00 | — | — | |
| SCHEMBL23601320 | 0.91 | MAT2A (0.35) | — | |
| SCHEMBL29909227 | 0.89 | ABCG2 (0.34) | — | |
| SCHEMBL31169405 | 0.86 | MAT2A (0.34) | — | |
| SCHEMBL23601049 | 0.86 | MAT2A (0.34) | — | |
| SCHEMBL23601523 | 0.83 | MAT2A (0.34) | — | |
| SCHEMBL23601518 | 0.81 | MAT2A (0.33) | — | |
| SCHEMBL23601437 | 0.81 | HSD17B1 (0.35) | — | |
| SCHEMBL23577347 | 0.80 | MAT2A (0.32) | — | |
| SCHEMBL23577071 | 0.80 | MAT2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |