Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576961 | 1.00 | TP53 (0.35) | TP53MTNR1AMTNR1BAOC3ATM | |
| SCHEMBL23577153 | 0.88 | AOC3 (0.38) | TP53MTNR1AMTNR1BAOC3ATM | |
| SCHEMBL29909552 | 0.88 | AOC3 (0.38) | TP53MTNR1AMTNR1BAOC3ATM | |
| SCHEMBL29909015 | 0.87 | IDO1 (0.37) | TP53MTNR1AMTNR1BAOC3ATM | |
| SCHEMBL23576968 | 0.87 | TP53 (0.47) | TP53MTNR1AMTNR1BAOC3ATM | |
| SCHEMBL29909468 | 0.87 | TP53 (0.47) | TP53MTNR1AMTNR1BAOC3ATM | |
| SCHEMBL23577181 | 0.87 | IDO1 (0.37) | TP53MTNR1AMTNR1BAOC3ATM | |
| SCHEMBL23601408 | 0.86 | KMT2A (0.39) | TP53MTNR1AMTNR1BAOC3ATM | |
| SCHEMBL23576632 | 0.86 | ALDH1A1 (0.32) | ALDH1A1MAPTDHODH | |
| SCHEMBL29909110 | 0.86 | KMT2A (0.39) | TP53MTNR1AMTNR1BAOC3ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |