SCHEMBL29909625

SCHEMBL29909625

Fc1cc(F)c2c(Cl)nc(Cl)nc2c1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
AAK1 Q2M2I8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23577597 1.00 BCHE (0.31) BCHEACHEAAK1
SCHEMBL23577002 0.84 PDE2A (0.30)
SCHEMBL29909484 0.84 PDE2A (0.30)
SCHEMBL29021119 0.81 HTT (0.35)
SCHEMBL4018444 0.72 ALDH1A1 (0.32)
SCHEMBL3521904 0.72 ALDH1A1 (0.36) AAK1
SCHEMBL24806318 0.72
SCHEMBL30146527 0.72
SCHEMBL1995692 0.72 PARP1 (0.42) ACHE
SCHEMBL30836076 0.72 ALDH1A1 (0.36) AAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324767-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2024-07-12 CN disclosed
CN-115362003-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2022-11-18 CN disclosed
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed