SCHEMBL29909484

SCHEMBL29909484

Fc1cc(Cl)cc2nc(Cl)nc(Cl)c12

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 1/20 0.30
PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23577002 1.00 PDE2A (0.30) PDE2APDE10A
SCHEMBL29909625 0.84 BCHE (0.31)
SCHEMBL23577597 0.84 BCHE (0.31)
SCHEMBL29021119 0.81 HTT (0.35)
SCHEMBL3672267 0.79 ALDH1A1 (0.35)
SCHEMBL28130489 0.76 HTT (0.33)
SCHEMBL1995692 0.76 PARP1 (0.42)
SCHEMBL29909242 0.76 PARP1 (0.42)
SCHEMBL24815913 0.72 TNF (0.33)
SCHEMBL23577134 0.72 TNKS (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324767-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2024-07-12 CN disclosed
CN-115362003-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2022-11-18 CN disclosed
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed