Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.38 |
| ▸ | PDE5A | O76074 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576729 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2TSHRALDH1A1POLBKDM4E | |
| SCHEMBL29909532 | 0.88 | ABCG2 (0.42) | SMN1; SMN2TSHRALDH1A1ABCG2PDE5A | |
| SCHEMBL23576805 | 0.88 | ABCG2 (0.42) | SMN1; SMN2TSHRALDH1A1ABCG2PDE5A | |
| SCHEMBL23577235 | 0.88 | ABCG2 (0.37) | SMN1; SMN2TSHRALDH1A1POLBKDM4E | |
| SCHEMBL23578033 | 0.88 | PDE5A (0.44) | SMN1; SMN2TSHRALDH1A1POLBKDM4E | |
| SCHEMBL29909130 | 0.87 | HTR7 (0.40) | TSHRALDH1A1HPGDHSD17B10ABCG2 | |
| SCHEMBL23576941 | 0.87 | HTR7 (0.40) | TSHRALDH1A1HPGDHSD17B10ABCG2 | |
| SCHEMBL29909882 | 0.86 | ALDH1A1 (0.39) | SMN1; SMN2TSHRALDH1A1POLBKDM4E | |
| SCHEMBL23578009 | 0.86 | ALDH1A1 (0.39) | SMN1; SMN2TSHRALDH1A1POLBKDM4E | |
| SCHEMBL23577241 | 0.84 | MAPT (0.43) | SMN1; SMN2TSHRALDH1A1ABCG2PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |