Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23578003 | 1.00 | ABCG2 (0.43) | ABCG2HRH4HRH3EGFRKEAP1 | |
| SCHEMBL23601765 | 0.89 | ABCG2 (0.44) | ABCG2HRH4HRH3EGFRHTT | |
| SCHEMBL30014094 | 0.89 | ABCG2 (0.47) | ABCG2HRH4HRH3HTTMAPT | |
| SCHEMBL23577151 | 0.89 | ABCG2 (0.47) | ABCG2HRH4HRH3HTTMAPT | |
| SCHEMBL24721496 | 0.88 | ABCG2 (0.43) | ABCG2HRH4HRH3EGFRKEAP1 | |
| SCHEMBL29909184 | 0.87 | ABCG2 (0.52) | ABCG2HRH4HRH3KEAP1NFE2L2 | |
| SCHEMBL23576737 | 0.87 | ABCG2 (0.52) | ABCG2HRH4HRH3KEAP1NFE2L2 | |
| SCHEMBL29909626 | 0.86 | ABCG2 (0.43) | ABCG2HRH4HRH3HTTMAPT | |
| SCHEMBL23578002 | 0.86 | ABCG2 (0.43) | ABCG2HRH4HRH3HTTMAPT | |
| SCHEMBL23578021 | 0.85 | ABCG2 (0.45) | ABCG2HRH4HRH3KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |