Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.33 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23578002 | 1.00 | ABCG2 (0.43) | ABCG2HRH4HRH3CNR2MAPT | |
| SCHEMBL23577151 | 0.91 | ABCG2 (0.47) | ABCG2HRH4HRH3MAPTHTT | |
| SCHEMBL30014094 | 0.91 | ABCG2 (0.47) | ABCG2HRH4HRH3MAPTHTT | |
| SCHEMBL29909184 | 0.87 | ABCG2 (0.52) | ABCG2HRH4HRH3MAPTHTT | |
| SCHEMBL23576737 | 0.87 | ABCG2 (0.52) | ABCG2HRH4HRH3MAPTHTT | |
| SCHEMBL23601765 | 0.87 | ABCG2 (0.44) | ABCG2HRH4HRH3MAPTHTT | |
| SCHEMBL29909685 | 0.86 | ABCG2 (0.43) | ABCG2HRH4HRH3MAPTHTT | |
| SCHEMBL23578003 | 0.86 | ABCG2 (0.43) | ABCG2HRH4HRH3MAPTHTT | |
| SCHEMBL24721496 | 0.86 | ABCG2 (0.43) | ABCG2HRH4HRH3MAPTHTT | |
| SCHEMBL23577113 | 0.85 | SIGMAR1 (0.41) | ABCG2HRH4HRH3CNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |