Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577277 | 1.00 | TP53 (0.41) | TP53KMT2AMGLLMTNR1AMTNR1B | |
| SCHEMBL29909291 | 0.90 | MGLL (0.36) | TP53KMT2AMGLLALDH1A1TSHR | |
| SCHEMBL23576658 | 0.90 | MGLL (0.36) | TP53KMT2AMGLLALDH1A1TSHR | |
| SCHEMBL23601577 | 0.89 | TP53 (0.39) | TP53MGLL | |
| SCHEMBL23576866 | 0.88 | MGLL (0.35) | TP53MGLL | |
| SCHEMBL29909218 | 0.88 | MGLL (0.35) | TP53MGLL | |
| SCHEMBL24721227 | 0.87 | TP53 (0.41) | TP53KMT2AALDH1A1TSPO | |
| SCHEMBL23600785 | 0.86 | TP53 (0.37) | TP53ALDH1A1 | |
| SCHEMBL23576965 | 0.86 | TP53 (0.37) | TP53KMT2AALDH1A1HPGD | |
| SCHEMBL23576643 | 0.86 | NPM1 (0.39) | TP53ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |