Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576658 | 1.00 | MGLL (0.36) | MGLLTP53SMN1; SMN2MAP2K4DHODH | |
| SCHEMBL23601577 | 0.92 | TP53 (0.39) | MGLLTP53SMN1; SMN2FYNMAPT | |
| SCHEMBL23577277 | 0.90 | TP53 (0.41) | MGLLTP53KMT2AALDH1A1TSHR | |
| SCHEMBL29909716 | 0.90 | TP53 (0.41) | MGLLTP53KMT2AALDH1A1TSHR | |
| SCHEMBL29909218 | 0.90 | MGLL (0.35) | MGLLTP53SMN1; SMN2FYNFGFR1 | |
| SCHEMBL23576866 | 0.90 | MGLL (0.35) | MGLLTP53SMN1; SMN2FYNFGFR1 | |
| SCHEMBL29909017 | 0.87 | AOC3 (0.38) | MGLLTP53FYNMAPTKMT2A | |
| SCHEMBL23600461 | 0.87 | AOC3 (0.38) | MGLLTP53FYNMAPTKMT2A | |
| SCHEMBL23576865 | 0.85 | MAPT (0.33) | TP53SMN1; SMN2DHODHMAPTKMT2A | |
| SCHEMBL23577190 | 0.85 | MAT2A (0.37) | TP53SMN1; SMN2MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |