Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.35 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576674 | 1.00 | SLC6A4 (0.35) | SLC6A4SLC6A3SLC6A2PBKFNTA | |
| SCHEMBL29909787 | 0.92 | FNTA (0.33) | FNTAFNTBMAT2ATP53MAPT | |
| SCHEMBL23577586 | 0.92 | FNTA (0.34) | SLC6A4SLC6A3SLC6A2PBKFNTA | |
| SCHEMBL23578133 | 0.92 | FNTA (0.33) | FNTAFNTBMAT2ATP53MAPT | |
| SCHEMBL29909830 | 0.92 | FNTA (0.34) | SLC6A4SLC6A3SLC6A2PBKFNTA | |
| SCHEMBL23576631 | 0.87 | MCHR1 (0.39) | — | |
| SCHEMBL29909768 | 0.87 | FNTA (0.40) | FNTAFNTBMAT2ATP53MAPT | |
| SCHEMBL23601235 | 0.87 | FNTA (0.40) | FNTAFNTBMAT2ATP53MAPT | |
| SCHEMBL23601231 | 0.85 | ALDH1A1 (0.33) | FNTAFNTBMAT2AHSD11B1 | |
| SCHEMBL31169411 | 0.85 | ALDH1A1 (0.33) | FNTAFNTBMAT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |