Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 6/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP7 | P09237 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577186 | 1.00 | RORC (0.35) | RORCFNTAFNTBEEDSUZ12 | |
| SCHEMBL23601032 | 0.90 | RORC (0.40) | RORCFNTAFNTBSCDGABRA2 | |
| SCHEMBL29909502 | 0.90 | RORC (0.37) | RORCFNTAFNTBMAT2APRMT5 | |
| SCHEMBL23577050 | 0.90 | RORC (0.37) | RORCFNTAFNTBMAT2APRMT5 | |
| SCHEMBL23601424 | 0.89 | RORC (0.39) | RORCFNTAFNTBMMP2MMP9 | |
| SCHEMBL31169425 | 0.89 | ALDH1A1 (0.39) | RORCFNTAFNTBMAT2APRMT5 | |
| SCHEMBL31229437 | 0.89 | RORC (0.39) | RORCFNTAFNTBMMP2MMP9 | |
| SCHEMBL23578155 | 0.89 | ALDH1A1 (0.39) | RORCFNTAFNTBMAT2APRMT5 | |
| SCHEMBL23601235 | 0.89 | FNTA (0.40) | FNTAFNTBMAT2APRMT5CYP1A2 | |
| SCHEMBL29909768 | 0.89 | FNTA (0.40) | FNTAFNTBMAT2APRMT5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |