SCHEMBL29909902

SCHEMBL29909902

CN(c1cccc(C#CC(C)(C)S(C)(=O)=O)c1)c1nc2nncn2c2cc(S(C)(=O)=O)ccc12

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23577117 1.00 PDE4B (0.30) PDE4B
SCHEMBL23577432 0.93
SCHEMBL29909667 0.93
SCHEMBL23601649 0.90 PTGDR2 (0.35)
SCHEMBL23576706 0.81 PTGS2 (0.38)
SCHEMBL29909045 0.81 PTGS2 (0.38)
SCHEMBL23577251 0.81 PAK4 (0.35)
SCHEMBL23601040 0.79 FNTA (0.34)
SCHEMBL23601039 0.78 PTGES (0.36)
SCHEMBL23601286 0.78 FNTA (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4445902-A2 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2024-10-16 EP disclosed
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed