Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 10/20 | 0.31 |
| ▸ | BRAF | P15056 | 9/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1332954 | 1.00 | FGFR1 (0.33) | FGFR1DDR2RARBRARARARG | |
| SCHEMBL12573708 | 1.00 | FGFR1 (0.33) | FGFR1DDR2RARBRARARARG | |
| SCHEMBL2015558 | 0.95 | FGFR1 (0.34) | FGFR1DDR2RARBRARARARG | |
| SCHEMBL12634342 | 0.95 | FGFR1 (0.34) | FGFR1DDR2RARBRARARARG | |
| SCHEMBL1332389 | 0.92 | FGFR1 (0.35) | FGFR1DDR2RARBRARARARG | |
| SCHEMBL9968003 | 0.92 | FGFR1 (0.35) | FGFR1DDR2RARBRARARARG | |
| SCHEMBL12573739 | 0.91 | CTNNB1 (0.36) | RARBRARARARGHTR2ADRD3 | |
| SCHEMBL1334089 | 0.90 | TRPA1 (0.34) | P2RY14LMNAMAPT | |
| SCHEMBL16033535 | 0.88 | RARB (0.33) | FGFR1DDR2RARBRARARARG | |
| SCHEMBL12634399 | 0.88 | NPC1 (0.34) | FGFR1DDR2P2RY14HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718755-B1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL INC (US) | 2024-05-29 | — | — | EP | disclosed |
| EP-2895896-B1 | A PHOTOCHROMIC ARTICLE HAVING AT LEAST PARTIALLY CROSSED POLARIZED PHOTOCHROMIC-DICHROIC AND FIXED-POLARIZED LAYERS | TRANSITIONS OPTICAL INC (US) | 2022-11-02 | — | — | EP | disclosed |