Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 6/20 | 0.34 |
| ▸ | BRAF | P15056 | 5/20 | 0.34 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9968003 | 1.00 | FGFR1 (0.35) | FGFR1DDR2RARBRARARARG | |
| SCHEMBL2015558 | 0.96 | FGFR1 (0.34) | FGFR1DDR2RARBRARARARG | |
| SCHEMBL12634342 | 0.96 | FGFR1 (0.34) | FGFR1DDR2RARBRARARARG | |
| SCHEMBL12573758 | 0.95 | FGFR1 (0.38) | FGFR1DDR2RARBRAF1BRAF | |
| SCHEMBL2019117 | 0.95 | FGFR1 (0.38) | FGFR1DDR2RARBRAF1BRAF | |
| SCHEMBL1332426 | 0.94 | MAPT (0.35) | P2RY14RAF1MCHR1LMNAMAPT | |
| SCHEMBL12573754 | 0.94 | MAPT (0.35) | P2RY14RAF1MCHR1LMNAMAPT | |
| SCHEMBL12573708 | 0.92 | FGFR1 (0.33) | FGFR1DDR2RARBRARARARG | |
| SCHEMBL29910219 | 0.92 | FGFR1 (0.33) | FGFR1DDR2RARBRARARARG | |
| SCHEMBL1332954 | 0.92 | FGFR1 (0.33) | FGFR1DDR2RARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2652552-B9 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2016-02-17 | — | — | EP | claimed |
| EP-2652552-B1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2015-09-02 | — | — | EP | claimed |
| US-8545984-B2 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2013-10-01 | — | — | US | claimed |
| US-20110129678-A1 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2011-06-02 | — | — | US | claimed |
| EP-3368285-B1 | METHOD OF MAKING OPTICAL ARTICLES HAVING GRADIENT LIGHT INFLUENCING PROPERTIES | TRANSITIONS OPTICAL INC (US) | 2026-04-15 | — | — | EP | disclosed |
| EP-3368927-B1 | OPTICAL ARTICLE WITH GRADIENT LIGHT INFLUENCING PROPERTIES AND METHOD OF MAKING THE SAME | TRANSITIONS OPTICAL INC (US) | 2024-10-16 | — | — | EP | disclosed |
| US-12076951-B2 | Method of making optical articles having gradient light influencing properties | TRANSITIONS OPTICAL, INC. (US) | 2024-09-03 | — | — | US | disclosed |
| US-12055741-B2 | Optical articles and method of preparing the same | TRANSITIONS OPTICAL, INC. (US) | 2024-08-06 | — | — | US | disclosed |
| EP-2718755-B1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL INC (US) | 2024-05-29 | — | — | EP | disclosed |
| EP-3368926-B1 | A METHOD OF MAKING AN OPTICAL ARTICLE WITH AN INKJET PRINTING DEVICE | TRANSITIONS OPTICAL LTD (IE) | 2024-03-06 | — | — | EP | disclosed |
| EP-2718754-B1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL INC (US) | 2024-01-24 | — | — | EP | disclosed |
| US-11714220-B2 | Optical article with gradient light influencing properties and method of making the same | TRANSITIONS OPTICAL, INC. (US) | 2023-08-01 | — | — | US | disclosed |
| US-8649081-B1 | Photochromic article having two at least partially crossed photochromic-dichroic layers | TRANSITIONS OPTICAL, INC. (US) | 2014-02-11 | — | — | US | disclosed |
| US-8582192-B2 | Polarizing photochromic articles | TRANSITIONS OPTICAL, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| EP-2652552-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | Transitions Optical, Inc. (US) | 2013-10-23 | — | — | EP | disclosed |
| US-8545015-B2 | Polarizing photochromic articles | TRANSITIONS OPTICAL, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-8545984-B2 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| WO-2012082299-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | WO | disclosed |
| US-20120120473-A1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 2012-05-17 | — | — | US | disclosed |
| US-20110279883-A1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110129678-A1 | Photochromic compounds and compositions | CRY2, CRY1, PPOX | FGFR1 3270/4885DDR2 1349/4885RARB 612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.