Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.80 |
| ▸ | MAOA | P21397 | 9/20 | 0.70 |
| ▸ | MAOB | P27338 | 8/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | MGAM | O43451 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SI | P14410 | 1/20 | 0.57 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.57 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.56 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20956524 | 1.00 | DHODH (0.80) | DHODHMAOAMAOBRAB9AMGAM | |
| SCHEMBL19631420 | 1.00 | DHODH (0.80) | DHODHMAOAMAOBRAB9AMGAM | |
| SCHEMBL19631414 | 0.89 | DHODH (0.95) | DHODHMAOAMAOBRAB9AMGAM | |
| SCHEMBL20956482 | 0.89 | DHODH (0.95) | DHODHMAOAMAOBRAB9AMGAM | |
| SCHEMBL20956442 | 0.89 | DHODH (1.00) | DHODHMAOAMAOBRAB9AMGAM | |
| SCHEMBL29911504 | 0.89 | DHODH (1.00) | DHODHMAOAMAOBRAB9AMGAM | |
| SCHEMBL19631441 | 0.89 | DHODH (1.00) | DHODHMAOAMAOBRAB9AMGAM | |
| SCHEMBL25614240 | 0.89 | MAOA (0.66) | DHODHMAOAMAOBRAB9ANPC1 | |
| SCHEMBL20956437 | 0.86 | DHODH (0.85) | DHODHRAB9AMGAMGAASI | |
| SCHEMBL19631410 | 0.86 | DHODH (0.85) | DHODHRAB9AMGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107375279-B | Use of novel thiazole derivatives for the treatment of inflammatory bowel disease | 华东理工大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-107459496-B | Use of thiazole derivatives for treating viral infections | 华东理工大学 | 2022-07-19 | — | — | CN | disclosed |