Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.80 |
| ▸ | MAOA | P21397 | 9/20 | 0.70 |
| ▸ | MAOB | P27338 | 8/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | MGAM | O43451 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SI | P14410 | 1/20 | 0.57 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.57 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.56 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29911542 | 1.00 | DHODH (0.80) | DHODHMAOAMAOBRAB9AMGAM | |
| SCHEMBL19631420 | 1.00 | DHODH (0.80) | DHODHMAOAMAOBRAB9AMGAM | |
| SCHEMBL19631414 | 0.89 | DHODH (0.95) | DHODHMAOAMAOBRAB9AMGAM | |
| SCHEMBL20956482 | 0.89 | DHODH (0.95) | DHODHMAOAMAOBRAB9AMGAM | |
| SCHEMBL20956442 | 0.89 | DHODH (1.00) | DHODHMAOAMAOBRAB9AMGAM | |
| SCHEMBL29911504 | 0.89 | DHODH (1.00) | DHODHMAOAMAOBRAB9AMGAM | |
| SCHEMBL19631441 | 0.89 | DHODH (1.00) | DHODHMAOAMAOBRAB9AMGAM | |
| SCHEMBL25614240 | 0.89 | MAOA (0.66) | DHODHMAOAMAOBRAB9ANPC1 | |
| SCHEMBL20956437 | 0.86 | DHODH (0.85) | DHODHRAB9AMGAMGAASI | |
| SCHEMBL19631410 | 0.86 | DHODH (0.85) | DHODHRAB9AMGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11590109-B2 | Applications of novel thiazole derivative in treating virus infection | INSTITUT PASTEUR OF SHANGHAI, CHINESE ACADEMY OF SCIENCES (CN) | 2023-02-28 | — | — | US | disclosed |
| US-11534427-B2 | Applications of novel thiazole derivative in treating inflammatory bowel diseases | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2022-12-27 | — | — | US | disclosed |
| CN-107375279-B | Use of novel thiazole derivatives for the treatment of inflammatory bowel disease | 华东理工大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-107459496-B | Use of thiazole derivatives for treating viral infections | 华东理工大学 | 2022-07-19 | — | — | CN | disclosed |
| US-20190290620-A1 | APPLICATIONS OF NOVEL THIAZOLE DERIVATIVE IN TREATING INFLAMMATORY BOWEL DISEASES | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-09-26 | — | — | US | disclosed |
| US-20190134008-A1 | APPLICATIONS OF NOVEL THIAZOLE DERIVATIVE IN TREATING VIRUS INFECTION | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11534427-B2 | Applications of novel thiazole derivative in treating inflammatory bowel diseases | FABP2, SLC10A2, ALPI | DHODH 803/4885MAOA 4074/4885MAOB 3732/4885 |
| US-20190290620-A1 | APPLICATIONS OF NOVEL THIAZOLE DERIVATIVE IN TREATING INFLAMMATORY BOWEL DISEASES | FABP2, SLC10A2, ALPI | DHODH 803/4885MAOA 4074/4885MAOB 3732/4885 |
| US-11590109-B2 | Applications of novel thiazole derivative in treating virus infection | HAVCR2, MAVS, EIF2AK2 | DHODH 1507/4885MAOA 4580/4885MAOB 4294/4885 |
| US-20190134008-A1 | APPLICATIONS OF NOVEL THIAZOLE DERIVATIVE IN TREATING VIRUS INFECTION | HAVCR2, MAVS, EIF2AK2 | DHODH 1507/4885MAOA 4580/4885MAOB 4294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.