Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509459 | 0.87 | LOXL2 (0.57) | SCN8ALOXL2CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL3671076 | 0.83 | LMNA (0.61) | LMNAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL30512338 | 0.83 | MAOA (0.61) | LMNAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL29912750 | 0.83 | LOXL2 (0.65) | SCN8ALOXL2CA12CA1CA2 | |
| SCHEMBL13985127 | 0.81 | LOXL2 (0.65) | SCN8ALOXL2LMNACA12CA1 | |
| SCHEMBL6759971 | 0.81 | SCN8A (0.52) | SCN8ALOXL2CA12CA1CA2 | |
| SCHEMBL2828109 | 0.81 | SCN8A (0.58) | SCN8ALOXL2LMNACA12CA1 | |
| SCHEMBL9885619 | 0.81 | SCN8A (0.55) | SCN8ALOXL2CA12CA1CA2 | |
| SCHEMBL9885618 | 0.81 | SCN8A (0.55) | SCN8ALOXL2CA12CA1CA2 | |
| SCHEMBL6764095 | 0.80 | SCN8A (0.55) | SCN8ALOXL2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437948-A | Selective histone deacetylase 6 inhibitors | 伊利诺伊大学董事会 | 2023-07-14 | — | — | CN | disclosed |