Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 10/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ADK | P55263 | 7/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29913169 | 0.84 | ADK (0.48) | RETGRM5ADK | |
| SCHEMBL24367881 | 0.73 | CDK2 (0.33) | — | |
| SCHEMBL20977360 | 0.73 | ALDH1A1 (0.33) | GRM5 | |
| SCHEMBL18050635 | 0.72 | CDK2 (0.35) | — | |
| SCHEMBL2966822 | 0.70 | ALDH1A1 (0.32) | — | |
| SCHEMBL5777500 | 0.70 | RET (0.39) | RETGRM5KCNH2ADK | |
| SCHEMBL30588906 | 0.69 | MAPKAPK2 (0.35) | — | |
| SCHEMBL24323977 | 0.69 | TLR7 (0.38) | — | |
| SCHEMBL13516914 | 0.69 | GRM5 (0.43) | GRM5 | |
| SCHEMBL4424103 | 0.69 | CSNK1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4329881-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-03-06 | — | — | EP | disclosed |
| CN-117642404-A | Small molecule modulators of glucocerebrosidase activity and uses thereof | 凡况生化公司 | 2024-03-01 | — | — | CN | disclosed |
| WO-2022232383-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2022-11-03 | — | — | WO | disclosed |