Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11472480 | 0.89 | ABCG2 (0.56) | NFE2L2KMT2ALMNAHPGDKDM4E | |
| SCHEMBL11472479 | 0.89 | ABCG2 (0.56) | NFE2L2KMT2ALMNAHPGDKDM4E | |
| SCHEMBL27980821 | 0.84 | HPGD (0.54) | NFE2L2KMT2ALMNAHPGDKDM4E | |
| SCHEMBL14218138 | 0.83 | LMNA (0.62) | NFE2L2KMT2ALMNAHPGDKDM4E | |
| SCHEMBL14190940 | 0.80 | KMT2A (0.61) | NFE2L2KMT2ALMNAHPGDKDM4E | |
| SCHEMBL4382984 | 0.80 | KMT2A (0.61) | NFE2L2KMT2ALMNAHPGDKDM4E | |
| SCHEMBL4378985 | 0.80 | LMNA (0.59) | NFE2L2KMT2ALMNAHPGDKDM4E | |
| SCHEMBL14190946 | 0.80 | LMNA (0.59) | NFE2L2KMT2ALMNAHPGDKDM4E | |
| SCHEMBL2831501 | 0.80 | HPGD (0.61) | NFE2L2KMT2ALMNAHPGDKDM4E | |
| SCHEMBL2744353 | 0.79 | NFE2L2 (1.00) | NFE2L2KMT2ALMNAKDM4ECYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110498761-B | Application of acetyl amantadine piperazine (pyridine) compound as cerebral nerve protective agent | 上海医药工业研究院 | 2022-09-13 | — | — | CN | claimed |
| CN-110498761-B | Application of acetyl amantadine piperazine (pyridine) compound as cerebral nerve protective agent | 上海医药工业研究院 | 2022-09-13 | — | — | CN | disclosed |