SCHEMBL29913402

SCHEMBL29913402

CC1(C)NC(=O)N(c2cnc(Oc3cccc4c3C(C)(C)CO4)cn2)C1=O

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 5/20 0.35
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21857964 1.00 AR (0.35) ARHTT
SCHEMBL21857956 0.90 AR (0.34) ARHTT
SCHEMBL21857898 0.89
SCHEMBL29913479 0.89
SCHEMBL30939546 0.86 AR (0.42) ARHTT
SCHEMBL9901069 0.86 AR (0.42) ARHTT
SCHEMBL21857668 0.84 AR (0.32) AR
SCHEMBL9901048 0.82 AR (0.41) ARHTT
SCHEMBL30939572 0.82 AR (0.41) ARHTT
SCHEMBL21953283 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115066424-B Kv3 modulators 奥蒂福尼疗法有限公司 2024-12-27 CN claimed
EP-3867247-B1 NOVEL COMPOUNDS AUTIFONY THERAPEUTICS LTD (GB) 2024-07-24 EP claimed
EP-4100402-A1 KV3 MODULATORS Autifony Therapeutics Limited (GB) 2022-12-14 EP claimed
CN-115066424-A Kv3 modulators 奥蒂福尼疗法有限公司 2022-09-16 CN claimed
US-20250304564-A1 NOVEL KV3 MODULATORS AUTIFONY THERAPEUTICS LTD (GB) 2025-10-02 US disclosed
US-12358901-B2 KV3 modulators AUTIFONY THERAPEUTICS LIMITED (GB) 2025-07-15 US disclosed
CN-115066424-B Kv3 modulators 奥蒂福尼疗法有限公司 2024-12-27 CN disclosed
EP-4100402-A1 KV3 MODULATORS Autifony Therapeutics Limited (GB) 2022-12-14 EP disclosed
CN-115066424-A Kv3 modulators 奥蒂福尼疗法有限公司 2022-09-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12358901-B2 KV3 modulators KCNN3, KCNA3, KCNH3 AR 1889/4885HTT 3638/4885
US-20250304564-A1 NOVEL KV3 MODULATORS KCNN3, KCNA3, KCND3 AR 2073/4885HTT 3668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.