Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MIF | P14174 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | GLA | P06280 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871071 | 0.88 | MAOA (0.57) | MAOBPOLBKDM4EGLAGAA | |
| SCHEMBL220708 | 0.84 | HSD17B3 (0.65) | HSD17B3MAOBPOLBMIFMEN1 | |
| SCHEMBL30405545 | 0.84 | HSD17B3 (0.65) | HSD17B3MAOBPOLBMIFMEN1 | |
| SCHEMBL29066603 | 0.81 | ESR2 (0.61) | HSD17B3POLBMIFMEN1KMT2A | |
| SCHEMBL15082511 | 0.80 | HSD17B3 (0.59) | HSD17B3MAOBPOLBMIFMEN1 | |
| SCHEMBL16283606 | 0.80 | POLB (0.59) | HSD17B3MAOBPOLBMIFMEN1 | |
| SCHEMBL6037595 | 0.80 | POLB (0.59) | HSD17B3POLBMIFMEN1KMT2A | |
| SCHEMBL28164061 | 0.80 | POLB (0.59) | HSD17B3POLBMIFMEN1KMT2A | |
| SCHEMBL15065807 | 0.80 | MAOB (0.56) | MAOBPOLBMEN1KMT2AKDM4E | |
| SCHEMBL15084975 | 0.78 | POLB (0.58) | HSD17B3POLBMIFMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220380331-A1 | TREATMENT OF CONDITIONS OF THE NERVOUS SYSTEM | THE UNIVERSITY OF LEEDS (GB) | 2022-12-01 | — | — | US | disclosed |
| CN-115023222-A | Treatment of neurological disorders | J·夸克 | 2022-09-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220380331-A1 | TREATMENT OF CONDITIONS OF THE NERVOUS SYSTEM | MGMT, PMP22, GAP43 | HSD17B3 474/4885MAOB 128/4885POLB 2460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.