Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21544112 | 1.00 | MAPK1 (0.34) | MAPK1ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL18893865 | 0.84 | ALDH1A1 (0.39) | MAPK1ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL29489718 | 0.84 | ALDH1A1 (0.39) | MAPK1ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL682486 | 0.81 | MAPK1 (0.43) | MAPK1ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL25382442 | 0.80 | HRH4 (0.40) | MAPK1ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL19458942 | 0.79 | MAPK1 (0.41) | MAPK1ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL983555 | 0.78 | GRIN2B (0.41) | MAPK1ALDH1A1TDP1L3MBTL1KMT2A | |
| SCHEMBL29525099 | 0.78 | GRIN2B (0.41) | MAPK1ALDH1A1TDP1L3MBTL1KMT2A | |
| SCHEMBL365350 | 0.76 | GRIN2B (0.37) | SLC6A4 | |
| SCHEMBL14994818 | 0.76 | KDM4E (0.37) | MAPK1ALDH1A1TDP1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110114343-B | Pyrazolopyrimidine compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2022-09-06 | — | — | CN | disclosed |