SCHEMBL682486

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL131996	0.90	ALDH1A1 (0.43)	MAPK1L3MBTL1ALDH1A1TDP1TSHR
	SCHEMBL30697962	0.88	PDE4B (0.46)	MAPK1TDP1TSHRSLC6A4LMNA
	SCHEMBL2410034	0.88	PDE4B (0.46)	MAPK1TDP1TSHRSLC6A4LMNA
	SCHEMBL873386	0.88	PDE4A (0.46)	MAPK1L3MBTL1TDP1TSHRLMNA
	SCHEMBL19458942	0.84	MAPK1 (0.41)	MAPK1L3MBTL1ALDH1A1TDP1TSHR
	SCHEMBL127226	0.83	SLC6A4 (0.48)	SLC6A4PDE4APDE4BPDE4CPDE4D
	SCHEMBL3132506	0.83	TSHR (0.50)	MAPK1ALDH1A1TSHRLMNAHPGD
	SCHEMBL983555	0.83	GRIN2B (0.41)	MAPK1L3MBTL1ALDH1A1TDP1SLC6A4
	SCHEMBL29525099	0.83	GRIN2B (0.41)	MAPK1L3MBTL1ALDH1A1TDP1SLC6A4
	SCHEMBL246292	0.83	SLC6A4 (0.47)	MAPK1L3MBTL1ALDH1A1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.