Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | ADCY2 | Q08462 | 2/20 | 0.41 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.41 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.41 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.41 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.41 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.41 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.41 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.41 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL650257 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL6167302 | 0.95 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL1535914 | 0.81 | MAPT (0.59) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL30450721 | 0.81 | GRIN2D (0.40) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL14035592 | 0.81 | GRIN2D (0.40) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL10703643 | 0.78 | DRD1 (0.54) | HTR2AHTR2CADCY2DRD1DRD2 | |
| SCHEMBL29181736 | 0.78 | MAOA (0.53) | ALDH1A1KDM4EMEN1PKMKMT2A | |
| SCHEMBL30811403 | 0.78 | MAOA (0.53) | ALDH1A1KDM4EMEN1PKMKMT2A | |
| Bromide SCHEMBL10703209 | 0.76 | DRD1 (0.55) | HTR2AHTR2CADCY2DRD1DRD2 | |
| SCHEMBL6568351 | 0.75 | MAPT (0.67) | ALDH1A1MAPTKDM4EMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344325-A | PI3K selective inhibitors | 轩竹生物科技股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118251393-A | Novel substituted sulfonylurea compounds as inhibitors of interleukin-1 activity | 唯久生物技术(苏州)有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-110114343-B | Pyrazolopyrimidine compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2022-09-06 | — | — | CN | disclosed |