Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 12/20 | 0.44 |
| ▸ | PARP1 | P09874 | 6/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PARP11 | Q9NR21 | 8/20 | 0.41 |
| ▸ | GRM5 | P41594 | 6/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29914423 | 0.85 | PARP10 (0.46) | PARP10PARP1F7F3KDM4E | |
| SCHEMBL24681544 | 0.85 | PARP10 (0.46) | PARP10PARP1F7F3KDM4E | |
| SCHEMBL24680477 | 0.84 | PARP10 (0.44) | PARP10PARP1F7F3KDM4E | |
| SCHEMBL24681553 | 0.83 | KDM4E (0.41) | PARP10PARP1F7F3KDM4E | |
| SCHEMBL31167946 | 0.82 | KDM4E (0.42) | PARP10PARP1F7F3KDM4E | |
| SCHEMBL2052209 | 0.76 | PARP10 (0.54) | PARP10PARP1F7F3KDM4E | |
| SCHEMBL29676875 | 0.76 | PARP10 (0.54) | PARP10PARP1F7F3KDM4E | |
| SCHEMBL1636716 | 0.76 | PARP10 (0.54) | PARP10PARP1F7F3KDM4E | |
| SCHEMBL30720809 | 0.76 | PARP10 (0.54) | PARP10PARP1F7F3KDM4E | |
| SCHEMBL793729 | 0.75 | PARP10 (0.62) | PARP10PARP1F7F3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022226667-A1 | SUBSTITUTED AMINO PYRIDINE COMPOUNDS AS INHIBITORS OF THE HAEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2022-11-03 | — | — | WO | disclosed |