Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 11/20 | 0.54 |
| ▸ | PARP11 | Q9NR21 | 10/20 | 0.54 |
| ▸ | PARP1 | P09874 | 3/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1636716 | 1.00 | PARP10 (0.54) | PARP10PARP11PARP1PDPK1GRM5 | |
| SCHEMBL29964464 | 0.92 | PARP11 (0.44) | PARP10PARP11PARP1PDPK1GRM5 | |
| SCHEMBL12077902 | 0.92 | PARP11 (0.44) | PARP10PARP11PARP1PDPK1GRM5 | |
| SCHEMBL29676875 | 0.89 | PARP10 (0.54) | PARP10PARP11PARP1PDPK1KDM4E | |
| SCHEMBL2052209 | 0.89 | PARP10 (0.54) | PARP10PARP11PARP1PDPK1KDM4E | |
| SCHEMBL12078239 | 0.86 | PARP10 (0.38) | PARP10PARP11PARP1PDPK1GRM5 | |
| SCHEMBL274197 | 0.86 | ROCK1 (0.43) | GRM5 | |
| SCHEMBL15570438 | 0.84 | PARP10 (0.49) | PARP10PARP11PARP1PDPK1KDM4E | |
| SCHEMBL12077888 | 0.82 | LPL (0.37) | PARP10PARP11 | |
| SCHEMBL204451 | 0.80 | LPL (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117597340-A | Substituted amino-aza-heteroaryl compounds as inhibitors of hematopoietic progenitor kinase 1 (HPK 1) | 安大略省癌症研究所(OICR) | 2024-02-23 | — | — | CN | disclosed |