Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 10/20 | 0.54 |
| ▸ | PARP1 | P09874 | 6/20 | 0.54 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | PARP11 | Q9NR21 | 6/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PRF1 | P14222 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 2/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2052209 | 1.00 | PARP10 (0.54) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL15570438 | 0.95 | PARP10 (0.49) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL30720809 | 0.89 | PARP10 (0.54) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL1636716 | 0.89 | PARP10 (0.54) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL392410 | 0.86 | CLK4 (0.44) | PARP10PARP1BACE1PRF1LPL | |
| SCHEMBL29609304 | 0.86 | CLK4 (0.44) | PARP10PARP1BACE1PRF1LPL | |
| SCHEMBL29964464 | 0.81 | PARP11 (0.44) | PARP10PARP1PARP11PDPK1BACE1 | |
| SCHEMBL12077902 | 0.81 | PARP11 (0.44) | PARP10PARP1PARP11PDPK1BACE1 | |
| SCHEMBL24820904 | 0.80 | LPL (0.40) | BACE1LPLLIPG | |
| SCHEMBL1226405 | 0.80 | PBRM1 (0.45) | BACE1LPLLIPGPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4653437-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Innovo Therapeutics Inc. (KR) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024154979-A2 | NOVEL HETEROCYCLIC COMPOUNDS | 주식회사 이노보테라퓨틱스 | 2024-07-25 | — | — | WO | disclosed |
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |
| CN-114948963-A | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-08-30 | — | — | CN | disclosed |
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | disclosed |