Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24681006 | 1.00 | NPY5R (0.43) | NPY5RNOTUMPDE10APIK3CDPIK3R1 | |
| SCHEMBL29914569 | 1.00 | NPY5R (0.43) | NPY5RNOTUMPDE10APIK3CDPIK3R1 | |
| SCHEMBL24681623 | 1.00 | NPY5R (0.43) | NPY5RNOTUMPDE10APIK3CDPIK3R1 | |
| SCHEMBL29914554 | 0.84 | CHEK2 (0.46) | NPY5RNOTUMPIM1PIM3PIM2 | |
| SCHEMBL24681535 | 0.84 | CHEK2 (0.46) | NPY5RNOTUMPIM1PIM3PIM2 | |
| SCHEMBL24680787 | 0.81 | PDE10A (0.38) | NPY5RPDE10APIK3CDPIK3R1PIK3CA | |
| SCHEMBL29914530 | 0.81 | PDE10A (0.38) | NPY5RPDE10APIK3CDPIK3R1PIK3CA | |
| SCHEMBL24681279 | 0.81 | PDE10A (0.38) | NPY5RPDE10APIK3CDPIK3R1PIK3CA | |
| SCHEMBL29914526 | 0.81 | PDE10A (0.38) | NPY5RPDE10APIK3CDPIK3R1PIK3CA | |
| SCHEMBL25966654 | 0.80 | HTR2A (0.41) | NPY5RNOTUMPIK3CDPIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022226667-A1 | SUBSTITUTED AMINO PYRIDINE COMPOUNDS AS INHIBITORS OF THE HAEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2022-11-03 | — | — | WO | disclosed |