Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | ADH1B | P00325 | 2/20 | 0.40 |
| ▸ | ADH1C | P00326 | 2/20 | 0.40 |
| ▸ | ADH1A | P07327 | 2/20 | 0.40 |
| ▸ | ADH4 | P08319 | 2/20 | 0.40 |
| ▸ | ADH7 | P40394 | 2/20 | 0.40 |
| ▸ | FDPS | P14324 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1110041 | 1.00 | CYP3A4 (0.47) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL27855009 | 1.00 | CYP3A4 (0.47) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL28017693 | 1.00 | CYP3A4 (0.47) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL28278270 | 0.98 | CYP3A4 (0.46) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL28235133 | 0.98 | CYP3A4 (0.46) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL3030456 | 0.98 | CYP3A4 (0.48) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL10527252 | 0.93 | PRSS1 (0.42) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL25044109 | 0.92 | LMNA (0.45) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL7209541 | 0.92 | LMNA (0.45) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 | |
| SCHEMBL96308 | 0.92 | CYP3A4 (0.55) | CYP3A4L3MBTL1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324272-B2 | Levodopa dimethyl-substituted diester prodrugs, compositions, and methods of use | XENOPORT, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-20100173992-A1 | LEVODOPA DIMETHYL-SUBSTITUTED DIESTER PRODRUGS, COMPOSITIONS, AND METHODS OF USE | XENOPORT, INC. (US) | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173992-A1 | LEVODOPA DIMETHYL-SUBSTITUTED DIESTER PRODRUGS, COMPOSITIONS, AND METHODS OF USE | COMT, DDT, DDC | CYP3A4 417/4885L3MBTL1 297/4885PRSS1 1796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.