SCHEMBL29915464

SCHEMBL29915464

NCCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](N)CO)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 1/20 0.51
▸ GSR P00390 1/20 0.47
▸ NMT1 P30419 5/20 0.47
▸ NMT2 O60551 4/20 0.47
▸ TLR2 O60603 1/20 0.45
▸ CPB2 Q96IY4 5/20 0.44
▸ SLC15A2 Q16348 1/20 0.44
▸ SLC6A5 Q9Y345 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29630712 1.00 FOLH1 (0.51) FOLH1GSRNMT1NMT2TLR2
SCHEMBL29591207 0.98 FOLH1 (0.50) FOLH1GSRNMT1NMT2TLR2
SCHEMBL30373815 0.98 FOLH1 (0.50) FOLH1GSRNMT1NMT2TLR2
SCHEMBL29669224 0.98 FOLH1 (0.50) FOLH1GSRNMT1NMT2TLR2
SCHEMBL29630412 0.98 FOLH1 (0.50) FOLH1GSRNMT1NMT2TLR2
SCHEMBL29630730 0.98 FOLH1 (0.50) FOLH1GSRNMT1NMT2TLR2
SCHEMBL30445726 0.95 NMT1 (0.49) FOLH1GSRNMT1NMT2TLR2
SCHEMBL30336991 0.95 FOLH1 (0.53) FOLH1GSRNMT1NMT2TLR2
SCHEMBL30373236 0.95 FOLH1 (0.53) FOLH1GSRNMT1NMT2TLR2
SCHEMBL18806290 0.95 FOLH1 (0.55) FOLH1GSRCPB2SLC15A2SLC6A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240353410-A1 FRET ENZYMATIC SUBSTRATE AND USES THEREOF IN LIVER CANCER URTESTE S.A. (PL) 2024-10-24 — — US disclosed
EP-4427041-A1 FRET ENZYMATIC SUBSTRATE AND USES THEREOF IN LIVER CANCER Urteste S.A. (PL) 2024-09-11 — — EP disclosed
CN-118202246-A FRET enzyme substrate and application thereof in liver cancer 尔特斯特公司 2024-06-14 — — CN disclosed
WO-2023080800-A1 FRET ENZYMATIC SUBSTRATE AND USES THEREOF IN LIVER CANCER. URTESTE S.A. (PL) 2023-05-11 — — WO disclosed
US-20230123431-A1 METABOLIC ENGINEERING FOR PRODUCTION OF LIPOIC ACID NATIONAL UNIVERSITY OF SINGAPORE (SG) 2023-04-20 — — US disclosed
US-11566256-B2 Polynucleotides and polypeptides in plants MENDEL BIOTECHNOLOGY, INC. (US) 2023-01-31 — — US disclosed
CN-115605579-A Metabolic engineering for the production of lipoic acid 新加坡国立大学(SG) 2023-01-13 — — CN disclosed
US-20220325072-A1 ZWITTERIONIC CROSSLINKERS, HYDROGELS COMPRISING ZWITTERIONIC CROSSLINKERS, AND METHODS FOR MAKING AND USING UNIVERSITY OF IDAHO 2022-10-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220325072-A1 ZWITTERIONIC CROSSLINKERS, HYDROGELS COMPRISING ZWITTERIONIC CROSSLINKERS, AND METHODS FOR MAKING AND USING ASS1, GFER, ASIC1 FOLH1 3483/4885GSR 1926/4885NMT1 3435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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